A GUIDE TO CANNABIDIOL
Cannabidiol is an element that is naturally derived from the leaves, stalks and flowers of the Hemp plant. These components are extracted (pressed – much like olive oil) into CBD oil. As technology advances scientific processes; our understanding of the benefits of Cannabidiol products is rapidly expanding. We are now able to extract JUST the CBD only – (trace THC) providing you around the clock relief, without feeling “stoned” or burned out all day. CDB oils can help manage daily life AND meet your needs for pain or anxiety therapy.
Cannabidiol (CBD for short) is a phytocannabinoid derived directly from the hemp plant (the cousin of the marijuana plant). It has a 21-carbon terpenophenolic compound. This compound can be produced synthetically but is a natural production of a cannabidiolic acid precursor – formed after decarboxylation. It is just one of the 113 cannabinoids contained in cannabis plants. It is an active ingredient in cannabis, the second most prevalent. Empirical data from clinical research suggests that CBD can be used to address – chronic, inflammatory and neuropathic pain, anxiety, seizures, insomnia, cognition and movement disorders, nausea, fatigue, irritability and a wide variety of other health issues.
CBD reacts differently in the areas of the brain and nervous system that manage pain-sensation, memory, mood and more…without the psychoactive THC. You get relief without changing your state of mind. CBD doesn’t get the user high, but it can reduce chronic pain and inflammation and a growing body of research suggests it could be useful for anxiety, post-traumatic stress disorder and for drug withdrawal, cigarette smoking cessation and a host of maladies. In June of 2018, the FDA approved CBD for treating 2 rare types of Epilepsy. Research is on-going and clinical trials in the U.K. and Spain are in their 7th year.
According to a report from the World Health Organization, CBD has vastly different effects than those associated with THC. Medical News Today explains, “Marijuana contains both THC and CBD, and these compounds have different effects. THC is the compound that creates the mind altering high”. CBD, however, did not produce behavioral characteristics in laboratory studies conducted with mice. For example, those associated with activation of CB1, included but not limited to, suppression of locomotor activity hypothermia and antinociception. All studies with humans and animals suggest that CBD is the diametric opposite of THC in terms of effects. Animal models are indicative of stress, heart rate, and blood pressure reduction after ingestion of CBD. Under normal conditions CBD has no effect on the aforementioned biological functions.
THE ENDOCANNABINOID SYSTEM
The Endocannabinoid system is composed of endocannabinoids. It is an extremely complex biological regulatory system. Endocannabinoids are derivatives of fatty acids and produced naturally by our bodies. They cohere with cannabinoid receptors, which are part of the endocannabinoid signaling system. They are molecular mechanisms utilized for regulation of signaling events. These event’s, as of yet, are not completely understood.
Scientific research led to the landmark discovery of the Endocannabinoid system over 25 years ago. This is an extremely complicated web of cannabinoid receptors that are expressed throughout the nervous system; both central and peripheral. This “communication system” is conveyed on a cellular level. The data suggests that this network is a critical physiological component. Biochemical mechanisms (such as mood, anxiety etc.) are believed be regulated by it. Rockefeller University describes it as follows: “The central endocannabinoid system is a neuroactive lipid signaling system in the brain which acts to control neurotransmitter release. The expression patterns of this system throughout limbic regions of the brain ideally situate it to exert regulatory control over emotional behavior, mood and stress responsivity. A growing body of evidence unequivocally demonstrates that deficits in endocannabinoid signaling may result in depressive and anxiogenic behavioral responses”.
The Endocannabinoid system has been shown to respond to the ingestion of CBD. The symptoms of illnesses such as epilepsy, chronic inflammation, depression, multiple sclerosis, diabetes, rheumatoid arthritis, anxiety, and opioid withdrawal etc. appear to be reduced with CBD introduction. The Endocannabinoid system is not unique to human beings. All vertebrates and invertebrates exhibit cannabinoid receptors with an expressive function. These receptors are exceedingly abundant in the human body naturally. They outnumber even the neurotransmitter receptors responsible for the production of dopamine and serotonin.
Data has revealed that you get optimum results from cannabinoids and terpenes are when they are ingested together. Terpenes are oily substances whose production has been traced to the resin glands of plants (and even some animals). The therapeutic, harmonious effects of CBD are magnified as cannabis terpenes interact symbiotically. Scientists refer to this as the “entourage affect”. Cannabidiol, one of the premier compounds in cannabis, is believed to mitigate the psychoactive features of THC; such as psychosis.
Terpenes are chemicals within the cannabis plant. Terpenes are numerous in nature; these aromatic metabolites are responsible for the many fragrances associated with cannabis as well as flavor. They are made from the sticky Trichomes of the plant. The organic compounds play a significant role in cannabis and are believed to be beneficial in treating a number of physiological ailments. Furthermore, they have anti-inflammatory and antioxidant properties. Although more scientific data and research is needed to ascertain the full spectrum of benefits associated with the terpene profile, terpenes play a key role in modulating the effects of cannabis.
ONGOING STUDIES AND CBD INGESTION
Clinical studies have shown time and again, the extraordinary therapeutic benefits of CBD. One study has shown that the plant derivative aids the body in not producing the chemical that triggers inflammation. So, not only does CBD have anti-inflammatory properties, it’s actually a preventative measure as well. Data has shown it to be a neuro-protectant, as it retards neurodegeneration, beneficial to cognitive function. It can relieve diarrhea and ease vomiting. Studies have shown its positive effect on diabetes and how it can actually get cancer cells to destroy themselves. CBD has even been shown to keep you alert in low doses, and help you sleep in higher ones. Therefore, you can tailor your dosage to suit your individual needs.
CBD oil can be consumed several different ways, including ingested capsules and food products, vaporizing, tinctures, and topical creams. There are many CBD rich remedies, but no matter which CBD product you choose: each item has a panel label with the identity of the product, the amount of CBD it contains, the net weight or volume, ingredient list, instructions for use and any government warning statements. This helps guarantee that you get what you paid for and reminds you that you ARE dealing w/a reputable company in CBDHempWise.
Disclaimer: The open resource material compiled here is provided to our customers as a courtesy, the information is meant simply to be an introduction/overview to Cannabidiol. It is not the intent of this website to be a substitute for data provided by scientific and medical professionals. As with the ingestion of any new substance, it is always prudent to consult your physician